Like ICA, CASEE is governed by the CASEE General Assembly, which is made up of Rectors and Deans or other duly appointed representatives of all member institutions. CASEE is a Standing Committee of ICA, the Association for European Life Science Universities. The General Assembly elects the CASEE Board, which is responsible for the general administration of the network and develops the network's strategy and objectives. The Board reports to the annual meeting of the ICA General Assembly.
The execution of the policy is delegated to the Executive Committee (ExCo). One of the members is the Secretary General, who is appointed by the Board.
The modus operandi of CASEE is determined by the CASEE Statutes.
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CASEE BOARD
| Name | Role | University | Member since (reelected) |
| Michal Lošťák | CASEE President | CZU | 2018 (2021) |
| Florin Stanica | CASEE Vice-President | USAMV Bucharest | 2019 (2022; VP from 2022) |
| Michal Zasada | CASEE Treasurer | SGGW | 2019 (2022; Trs. from 2021) |
| Muhamed Brka | member | UNSA | 2019 (2022) |
| Eva Schulev-Steindl | member | BOKU | 2022 |
| Dan Vodnar | member | USAMV Cluj-Napoca | 2022 |
| Ivica Kisić | member | Uni Zagreb | 2023 |
Presidency until July 2018:
- President of the CASEE network: Rector Prof. Martin Gerzabek, BOKU (from 2010 to 2018)
- Vice-President of the CASEE network: Rector Prof. Ing. Jiri Balík, CSc., from Czech University of Life Sciences, Prague (from 2010 to 2018)
- Treasurer of the CASEE network: Vice-Rector Prof. István Szabó, Szent István University Gödöllö, Agricultural Faculty (from 2010 to 2018)
Presidency from 2018 - 2021
- Vice-Rector Prof. Michal Lostak, Czech University of Life Sciences Prague
- Rector Hubert Hasenauer, University of Natural Resources and Life Sciences, Vienna
- Treasurer of the CASEE network: Vice-Rector Prof. István Szabó, Szent István University Gödöllö, Agricultural Faculty
Ordinary Board members:
- CASEE President: Prof. Michal Lostak, First Vice-Rector, Czech University of Life Sciences Prague; from 2018, reelected in 2021
- CASEE Vice-President: Prof. Florin Stanica, Vice-Rector, University of Agricultural Sciences and Veterinary Medicine Bucharest; from 2019; Vice-President from 2022
- CASEE Board member: Prof. Eva Schulev-Steindl, Rector, University of Natural Resources and Life Sciences, Vienna; from 2022
- CASEE Board Member: Prof. Michal Zasada, Vice-Rector, Warsaw University of Life Sciences; from 2019
- CASEE Board Member: Prof. Muhamed Brka, Dean, Faculty of Agriculture, University of Sarajevo, from 2019
- CASEE Board Member: Prof. Dan Vodnar, Vice-Rector, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, from 2022
- CASEE Board Member: Prof. Ivica Kisić, Dean, Faculty of Agriculture, University of Zagreb, from 2023
- Prof. Hubert Hasenauer, Rector, University of Natural Resources and Life Sciences Vienna (until 2022)
- Prof. Florian Borlea, Vice-Rector of USAMVBT Timisoara, Romania (until 2019)
- Prof. Marek Szyndel, Vice-Rector of WULS Warsaw University of Life Sciences, Poland (until 2019)
- Prof. Sasa Orlovic, Vice-Rector of UNS Novi Sad, Serbia (until 2019)
- Prof. Dr. Doru Pamfil, Rector of USAMV Cluj-Napoca, Romania (until 2019)
- Prof. Aleksa Bjeliš, Rector of the University of Zagreb, Croatia (until 2016)
- Prof. Miroslav Veskovic, DG JRC Brussels (until 2016)
- Prof. Dr. sc. Zoran Grgić, Dean of UNIZG University of Zagreb, Faculty of Agriculture (until 2021)